Gene name:
Thra (C-erba-alpha;Nr1a1) ;
Protein name:
Thyroid hormone receptor alpha ;
Alternative:
c-erbA-1 ;Nuclear receptor subfamily 1 group A member 1 ;c-erbA-alpha ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Probably interacts with SFPQ. Interacts with AKAP13 (By similarity). Interacts with C1D.
Function:
Nuclear hormone receptor. High affinity receptor for triiodothyronine. Isoform Alpha-deltaE6 does not bind DNA, inhibits the activity of isoform Alpha-1, and stimulates myoblast differentiation.
Subcellular Location:
Isoform Alpha-deltaE6
Cytoplasm
Sequesters isoform Alpha-1 into this compartment.
Protein Attributes:
50:
MEQKPSKVEC | GSDPEENSAR | SPDGKRKRKN | GQCPLKSSMS | GYIPSYLDKD |
100:
EQCVVCGDKA | TGYHYRCITC | EGCKGFFRRT | IQKNLHPTYS | CKYDSCCVID |
150:
KITRNQCQLC | RFKKCIAVGM | AMDLVLDDSK | RVAKRKLIEQ | NRERRRKEEM |
200:
IRSLQQRPEP | TPEEWDLIHV | ATEAHRSTNA | QGSHWKQRRK | FLPDDIGQSP |
250:
IVSMPDGDKV | DLEAFSEFTK | IITPAITRVV | DFAKKLPMFS | ELPCEDQIIL |
300:
LKGCCMEIMS | LRAAVRYDPE | SDTLTLSGEM | AVKREQLKNG | GLGVVSDAIF |
350:
ELGKSLSAFN | LDDTEVALLQ | AVLLMSTDRS | GLLCVDKIEK | SQEAYLLAFE |
400:
HYVNHRKHNI | PHFWPKLLMK | EREVQSSILY | KGAAAEGRPG | GSLGVHPEGQ |
450:
QLLGMHVVQG | PQVRQLEQQL | GEAGSLRGPV | LQHQSPKSPQ | QRLLELLHRS |
492:
GILHSRAVCG | EDDSSEASSL | SSSSDTEDTE | VCEDQAGKAA | SP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Pig
Chicken
Mouse
ELISA Kit for Mouse Thyroid hormone receptor alpha
ELISA Kit for Mouse Thyroid hormone receptor alpha
ELISA Kit for Mouse Thyroid hormone receptor alpha
ELISA Kit for Mouse Thyroid hormone receptor alpha
ELISA Kit for Mouse Thyroid hormone receptor alpha
CLIA Kit for Mouse Thyroid hormone receptor alpha
CLIA Kit for Mouse Thyroid hormone receptor alpha
CLIA Kit for Mouse Thyroid hormone receptor alpha
CLIA Kit for Mouse Thyroid hormone receptor alpha
CLIA Kit for Mouse Thyroid hormone receptor alpha
Polyclonal Antibody for Mouse Thyroid hormone receptor alpha
Polyclonal Antibody for Mouse Thyroid hormone receptor alpha
Polyclonal Antibody for Mouse Thyroid hormone receptor alpha
Polyclonal Antibody for Mouse Thyroid hormone receptor alpha
Polyclonal Antibody for Mouse Thyroid hormone receptor alpha
Monoclonal Antibody for Mouse Thyroid hormone receptor alpha
Monoclonal Antibody for Mouse Thyroid hormone receptor alpha
Monoclonal Antibody for Mouse Thyroid hormone receptor alpha
Monoclonal Antibody for Mouse Thyroid hormone receptor alpha
Monoclonal Antibody for Mouse Thyroid hormone receptor alpha
Protein for Mouse Thyroid hormone receptor alpha
Protein for Mouse Thyroid hormone receptor alpha
Protein for Mouse Thyroid hormone receptor alpha
Protein for Mouse Thyroid hormone receptor alpha
Protein for Mouse Thyroid hormone receptor alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA-1);NUCLEOTIDE SEQUENCE [MRNA] OF 1-452 (ISOFORMS ALPHA-2 AND ALPHA-3)
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C3H .
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Muscle .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA-1)
strain :
C3H .
tissue :
Testis .
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA-1)
strain :
C57BL/6J .
tissue :
Olfactory bulb .
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PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA-2)
strain :
C57BL/6 .
tissue :
Brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH C1D
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NCOA6
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING (ISOFORMS ALPHA-1 AND ALPHA-DELTAE6);POTENTIAL RNA EDITING OF ISOFORM ALPHA-DELTAE6;FUNCTION;TISSUE SPECIFICITY
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PER2